Emanuel de Sousa, an architect, and his finance sister Patricia de Sousa teamed up in 2012 to open Rosa Et Al, a six-room guesthouse in a 19th-century building in the arts district of Porto, Portugal, with a midcentury vibe, accented with unexpected homey touches (including afghan throws crocheted by Patricia). The hotel’s small concept shop offers design books, homemade limoncello, local Portuguese wines, and more; also on offer: wine tastings, special events, and workshops and retreats (including Knitting Mindfulness, focusing on crochet, tricot, embroidery, yoga, and meditation). We’re booking our tickets now.

Above: The communal lounge has an eclectic mix of vintage and new furniture.

Above: A communal kitchen.

Above: A Prouve Potence light hovers over the sinuous staircase.

Above: The suites have original wood beams and plasterwork ceilings.

Above: The third-floor Townhouse Suite is located in the attic overlooking Porto city rooftops; Patricia crocheted the traditional afghan.

Above: The brother/sister duo has stocked the rooms with made-in-Portugal elements; the mattresses and pillows are from Colunex, a high-end maker based in Paredes.

Above: The Townhouse Queen Suite on the second floor overlooks Rua do Rosario.

Above: A grouping of vintage midcentury furniture pieces in the Townhouse Queen Suite.

Above: A vintage-style clawfoot tub from Portuguese company Recor.

For more inspiration, go to Our Favorite Hotel in Porto, Portugal.